VX-702
p38MAPK抑制剂
VX-702
p38MAPK抑制剂
VX-702
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产品编号： CVR900250
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CAS号： 745833-23-2
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分子式：C19H12F4N4O2
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分子量：404.32
英文别名：
6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide
参考文献：
Kuliopulos, A. et al.: Thromb. Haemost., 92, 1387 (2004); Ding, C.: Curr. Opin. Invest. Drug, 7, 1020 (2006); Cohen, S. et al.: Curr. Opin. Rheumatol., 22, 330 (2010);
VX-702 is a p38 mitogen-activated protein kinase (MAPK) inhibitor. VX-702 had no effect on platelet aggregation induced by any of the p38 MAPK agonists. VX-702 has potential use in the treatment of inflammation, rheumatoid arthritis and cardiovascular diseases.
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