Tivozanib
VEGF受体酪氨酸激酶抑制剂；N-{2-氯-4-[(6,7-二甲氧基喹啉-4-基)氧]苯基}-3-(5-甲基异恶唑-3-基)脲
Tivozanib
VEGF受体酪氨酸激酶抑制剂；N-{2-氯-4-[(6,7-二甲氧基喹啉-4-基)氧]苯基}-3-(5-甲基异恶唑-3-基)脲
Tivozanib
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产品编号： CTR447205
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CAS号： 475108-18-0
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分子式：C22H19ClN4O5
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分子量：454.86
英文别名：
AV 951；KRN 951；Kil 8951
SMILES：
BrC1=CC=C(C(C2=CC=CS2)(O)C(OC2CC3[C@H]4O[C@H]4C([N+]3(C)C)C2)=O)S1
参考文献：
Nosov, D.A., et al.: J. Clinical. Oncol., 30, 1678 (2012); Pal, S.K., et al., Molec. Cancer. Thr, 11, 526 (2012);
Tivozanib is known as an oral VEGF receptor tyrosine kinase inhibitor, exhibiting antitumor effects towards renal cell carcinoma.. Tivozanib suppresses angiogenesis by selectively inhibiting against vascular endothelial growth factor.
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