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消旋去甲猪毛菜碱氢溴酸盐
消旋去甲猪毛菜碱氢溴酸盐;消旋猪毛菜酚氢溴酸盐
rac Salsolinol, Hydrobromide
  • 产品编号: CSR099995

  • CAS号: 59709-57-8

  • 分子式:C10H14BrNO2

  • 分子量:260.13

  • EINECES:202-804-9

英文别名:
1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
熔点:
183-185°C
可溶性:
DMSO, Methanol,
性状:
Off-White to Pale Yellow Solid
SMILES:
OC1C=CC(C(=O)O)=CC=1
储存条件:
Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
参考文献:
J. Pharmacol. Exp. Ther., 174, 401 (1970); Science, 167, 1749 (1970); Science, 167, 1005 (1970); Aust. J. Chem., 41, 483 (1988)
Salsolinol is derived from the neurotransmitter dopamine and acetaldehyde. Interest in this molecule comes from studies suggesting that it might be involved in alcohol addiction, as acetaldehyde is both a well recognized substrate for the Pictet-Spengler reaction and the primary metabolite of ethanol in the liver. It has further been suggested that acetaldehyde formed as a result of alcohol consumption might induce central changes in the metabolism of dopamine.
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