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普拉曲沙
普拉曲沙;10-炔丙基-10-脱氮杂氨基蝶呤
Pralatrexate
  • 产品编号: CPR700500

  • CAS号: 146464-95-1

  • 分子式:C23H23N7O5

  • 分子量:477.47

  • EINECES:234-062-7

英文别名:
10-Propargyl-10-deazaaminopterin; Folotyn; PDX
SMILES:
[K+].C[Si]([O-])(C)C
参考文献:
Krug, L.M. et al.: Clin. Cancer Res., 6, 3493 (2000); O'Connor, O.A. et al.: Br. J. Haematol., 139, 425 (2007); O'Connor, O.A. et al.: J. Clin. Oncol., 29, 1182 (2011);
An antifolate with high affinity for the reduced folate carrier-type 1, produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma.
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