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匹莫苯丹
消旋匹莫苯丹;DL-匹莫苯丹
rac Pimobendan
  • 产品编号: CPR447500

  • CAS号: 74150-27-9

  • 分子式:C19H18N4O2

  • 分子量:334.37

英文别名:
UD-CG 115;UD-CG 115BS;dl-Pimobendan
熔点:
249-251°C
可溶性:
DMSO, Methanol
性状:
White Solid
储存条件:
Refrigerator
参考文献:
Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.
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