N-(2-苯乙基)吲哚美辛酰胺
N-(2-苯乙基)吲哚美辛酰胺
N-(2-苯乙基)吲哚美辛酰胺
N-(2-Phenylethyl)indomethacin Amide
N-(2-苯乙基)吲哚美辛酰胺
N-(2-Phenylethyl)indomethacin Amide
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产品编号: CPR321250
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CAS号: 261766-32-9
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分子式:C27H25ClN2O3
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分子量:460.95
英文别名:
N-(2-Phenylethyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-N-(2-phenylethyl)-1H-indole-3-acetamide;
参考文献:
Kalgutkar, A.S., et al.: J. Med. Chem., 43, 2860 (2000)
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.06 uM and 0.125 uM, respectively.
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