NS-2028
sGC抑制剂；8-溴-1H,4H-[1,2,4]恶二唑并[3,4-c][1,4]苯并噁嗪-1-酮
NS-2028
sGC抑制剂；8-溴-1H,4H-[1,2,4]恶二唑并[3,4-c][1,4]苯并噁嗪-1-酮
NS-2028
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产品编号： CNR900200
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CAS号： 204326-43-2
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分子式：C9H5BrN2O3
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分子量：269.05
英文别名：
8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one
参考文献：
Olesen, et al.: Br. J. Pharmacol., 123, 299 (1998), von Wantoch Rekowski, et al.: Bioorg. Med. Chem. 18, 1288 (2010),
NS-2028 potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). NS-2028 blocks sGC activity in murine cerebellum induced by S-nitroso-glutathione and NMDA. NS-2028 inhibits VEGF-induced cGMP accumulation; abolishes VEGF-induced migration in postcapil
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