利马前列素
利马前列素
Limaprost
利马前列素
Limaprost
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产品编号： CLR461500
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CAS号： 74397-12-9
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分子式：C22H36O5
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分子量：380.52
英文别名：
(2E)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-2-heptenoic Acid; (2E,11α,13E,15S,17S)-11,15-Dihydroxy-17,20-
dimethyl-9-oxo-prosta-2,13-dien-1-oic Acid; 17S,20-Dimethyl-trans-Δ2-PGE1; ONO 1206; OP 1206;
SMILES：
CC1=CC2=C(C(C)(C)CCC2(C)C)C=C1C1(C2C=CC(C(O)=O)=CN=2)CC1
参考文献：
Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),
Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.
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