HX-630-d4
HX-630-d4
RXR激动剂内标物;4-(7,8,9,10-四氢-7,7,10,10-四甲基苯并[b]萘并[2,3-f][1,4]硫氮杂卓-12-基)苯甲酸-d4
HX-630-d4
RXR激动剂内标物;4-(7,8,9,10-四氢-7,7,10,10-四甲基苯并[b]萘并[2,3-f][1,4]硫氮杂卓-12-基)苯甲酸-d4
HX-630-d4
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产品编号: CHR674252
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CAS号: 1794787-53-3
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相关CAS号:188844-52-2(未标记)
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分子式:C28H23D4NO2S
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分子量:445.61
英文别名:
4-(7,8,9,10-tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl)benzoic Acid-d4
参考文献:
Haraguchi, G. et al.: J. Mol. Cell. Cardiol., 41, 885 (2006); Nishimaki-M. et al.: Biochem. Pharmacol., 76, 1006 (2008);
The labelled analogue of a nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It efficiently enhanced ABCA1 mRNA expression and apoA-I-dependent cellular cholesterol release in differentiated THP-1 cells.
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