富马酸单乙酯钙盐
富马酸单乙酯钙盐
Fumaric Acid Monoethyl Ester Calcium Salt
富马酸单乙酯钙盐
Fumaric Acid Monoethyl Ester Calcium Salt
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产品编号： CFR500386
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CAS号： 62008-22-4
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分子式：C6H7O4.1/2Ca
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分子量：163.16
英文别名：
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SMILES：
C1C(O)=CC2=C(C3(OC(C4C=C(C=CC3=4)NC(=S)NCCOP(=O)(O)OC[C@@H](COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)=O)C5C=CC(O)=CC=5O2)C=1
参考文献：
Hagedorn, M. et al.: Arch. Dermatol. Res., 254, 67 (1975); Thio, H.B. et al.: Br. J. Dermatol., 131, 856 (1994); Rostami-Yazdi, M. Arch. Dermatol. Res., 302, 531 (2010);
The calcium salt of Fumaric Acid Monoethyl Ester (F500385), an anti-psoriatic fumaric acid ester. Fumaric Acid Monoethyl Ester inhibited thymidine-14C incorporation into DNA by cultured human lymphocytes. Fumaric Acid Monoethyl Ester has been shown to evoke transient increase in intracellular free calcium concentration and inhibit proliferation of human keratinocytes.
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