MI-nc盐酸盐
MI-nc盐酸盐；6-乙基-4-[4-(1,3,4-噻二唑-2-基)-1-哌嗪基]噻吩并[2,3-d]嘧啶盐酸盐
MI-nc hydrochloride
MI-nc盐酸盐；6-乙基-4-[4-(1,3,4-噻二唑-2-基)-1-哌嗪基]噻吩并[2,3-d]嘧啶盐酸盐
MI-nc hydrochloride
-
产品编号： CER926745
-
CAS号： 1359873-45-2
-
分子式：C14H17ClN6S2
-
分子量：368.91
英文别名：
6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride
SMILES：
CC1=C(CC)C(=O)N2C(C(CCC2)O)=N1
参考文献：
Grembecka, J. et al.: Nat. Chem. Biol., 8, 277 (2012);
6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine is an inhibitor of fusion protein interaction of menin-mixed lineage leukemia (menin-MLL). Menin-MLL inhibitors downregulate the expression of target genes required for MLL fusion protein oncogenic activity and thus effectively reverse MLL fusion protein-mediated leukemic transformation.
搜索质检报告(COA)
搜索MSDS
