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17α-雌二醇
17α-雌二醇;α-雌二醇;17-表雌二醇
17α-Estradiol
  • 产品编号: CER887995

  • CAS号: 57-91-0

  • 分子式:C18H24O2

  • 分子量:272.38

英文别名:
(17α)-Estra-1,3,5(10)-triene-3,17-diol; 1,3,5-Estratriene-3,17α-diol; 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol; 17-Epiestradiol; 17α-Oestradiol; 3,17-Dihydroxyestratriene; 3,17α-Dihydroxyoestra-1,3,5(10)-triene; Alfatradiol; Epiestrol; Estra-1,3,5(10)-t
熔点:
210-219°C
可溶性:
Dioxane, Methanol
性状:
White Solid
SMILES:
CCCC(C(=O)O)CC
储存条件:
Refrigerator
参考文献:
Salole, E.G., Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstret. Gynecol., 156, 1289 (1987), Kuhnz, W., et al.: Arzneim.-Forsch., 43, 966 (1993),
Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.
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