依普利酮-d3
依普利酮-d3
Eplerenone-d3
依普利酮-d3
Eplerenone-d3
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产品编号： CER588777
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分子式：C24H27D3O6
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分子量：417.51
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EINECES：200-097-1
英文别名：
(7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; γ-Lactone 7-(Methyl-d3) Ester; CGP 30083-d3; Epoxymexrenone-d3; Inspra-d3; SC-66110-d3
熔点：
241-243°C
可溶性：
Chloroform
性状：
White Solid
SMILES：
CNCC(C1=CC=C(O)C(O)=C1)O.OC(C(C(C(=O)O)O)O)=O
参考文献：
de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),
Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
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