地塞米松磷酸酯
地塞米松前体；地塞米松磷酸酯
Dexamethasone Phosphate
地塞米松前体；地塞米松磷酸酯
Dexamethasone Phosphate
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产品编号： CDR298835
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CAS号： 312-93-6
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分子式：C22H30FO8P
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分子量：472.44
英文别名：
(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Phosphate; Betnelan Phosphate; Dexamethasone 21-Dihydrogen Phosphate; Dexamethasone 21-Phosph
熔点：
>173°C (dec.)
可溶性：
DMSO (Slightly), Methanol (Slightly)
性状：
灰白色至浅棕色固体
储存条件：
-20°C
参考文献：
Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),
A pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction.
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