4-去甲氧基-4-羟基阿哌沙班
阿哌沙班代谢物；4-去甲氧基-4-羟基阿哌沙班
4-Demethoxy-4-hydroxy Apixaban
阿哌沙班代谢物；4-去甲氧基-4-羟基阿哌沙班
4-Demethoxy-4-hydroxy Apixaban
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产品编号： CDR231405
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CAS号： 503612-76-8
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分子式：C24H23N5O4
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分子量：445.47
英文别名：
4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1-(4-Hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
熔点：
>250°C (dec.)
可溶性：
DMSO (Slightly), Methanol (Slightly, Heated)
性状：
白色固体
SMILES：
COCCOCO/N=C1\[C@H](C)C[C@@](C)(O)[C@H](O[C@@H]2O[C@H](C)C[C@H](NC)[C@H]2O)[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@H]\1C
储存条件：
冷藏
参考文献：
Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);
4-Demethoxy-4-hydroxy Apixaban is a metabolite of Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.
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