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β-皮酮四醇
皮质醇代谢物;β-皮酮四醇;β-皮甾酮四醇;β-可妥龙
β-Cortolone
  • 产品编号: CCR696285

  • CAS号: 667-66-3

  • 分子式:C21H34O5

  • 分子量:366.49

英文别名:
3α,17,20β,21-Tetrahydroxy-11-pregnanone; 5β-Pregnan-11-one, 3α,17,20β,21-tetrahydroxy- (7CI,8CI); 20β-Cortolone; 20β-Hexahydrocortisone; 3α,17,20β,21-Tetrahydroxy-5β-pregnan-11-one; 3α,17α,20β,21-Tetrahydroxy-5β-pregnan-11-one; 5β-Pregnan-3α,17α,20β,21-tetrol-11-one; 5β-Pregnane-3α,17α,20β,21-tetrol-11-one; NSC 56997
熔点:
249-258ºC
可溶性:
Chloroform (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly)
性状:
白色至灰白色固体
SMILES:
O=C1CCC2(C3C(O)CC4(C(CCC4C3CCC2=C1)(O)C(=O)O)C)C
储存条件:
冷藏
参考文献:
Fukushima, D.K., et. al.: Steroids, 35, 209 (1980); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol.,
β-Cortolone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
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