C6-神经酰胺
C6-神经酰胺
C6-神经酰胺;N-己酰-D-鞘氨醇;N-己酰鞘氨醇;己酰神经酰胺
C6 Ceramide
C6-神经酰胺;N-己酰-D-鞘氨醇;N-己酰鞘氨醇;己酰神经酰胺
C6 Ceramide
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产品编号: CCR262600
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CAS号: 124753-97-5
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分子式:C24H47NO3
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分子量:397.63
英文别名:
N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexanamide; N-Hexanoy-D-sphingosine; N-Hexanoylsphingosine; N-Caproyl-D-sphingosine; Caproyl Ceramide;
熔点:
76-77°C
可溶性:
Chloroform, Methanol
性状:
White to Off-White Solid
SMILES:
CCCCCCCCCCCCC/C=C/C(C(NC(CCCCC)=O)CO)O
储存条件:
-20°C
参考文献:
Liu, Z., et al.: J. Neurochem., 106, 2463 (2008), Heakal, Y., et al.: Mol. Cancer Res., 7, 724 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Mahdy, A., et al.: Mol. Ther., 17, 430 (2009),
A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
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