CAL-101
PI3K/mTOR通道抑制剂
CAL-101
PI3K/mTOR通道抑制剂
CAL-101
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产品编号： CCR124800
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CAS号： 870281-82-6
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分子式：C22H18FN7O
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分子量：415.42
英文别名：
5-Fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)propyl]-4(3H)-quinazolinone; CAL 101; Delalisib; GS 1101; Idelalisib; N6-[(S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl]adenine; Zydelig;
熔点：
250-252ºC
可溶性：
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Very Slightly, Heated)
性状：
Pale Brown Solid
SMILES：
N1C(NC(C2N(C3C=CC=CC=3)C(=O)C3C(=CC=CC=3F)N=2)CC)=C2C(NC=N2)=NC=1
储存条件：
冷藏
参考文献：
Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);
CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs.
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